Of all the clinical trials that are conducted and completed, only around half get published in academic journals. Trials with positive results are twice as likely to be published as others. This is according to a systematic review conducted in 2010 by the NHS NIHR Health Technology Assessment Programme (UK).
|Studies have repeatedly found Data from http://www.alltrials.net/wp-content/uploads/2013/01/Missing-trials-briefing-note.pdf|
Fortunately, there's a move afoot to get this situation corrected. All Trials Registered, All Results Reported is an initiative of Sense About Science, Bad Science, BMJ, James Lind Initiative, the Centre for Evidence-based Medicine and others aimed at getting 100% of clinical-trials research published. The group started a petition drive in January (you can sign the AllTrials petition here; and be sure to Tweet it with hashtag #AllTrials), and it has begun to get some traction in the industry. GlaxoSmithKline got behind the AllTrials campaign in February, saying it would publish all of its clinical trial data going back to the formation of GSK in 2000 when it merged with SmithKline Beecham. Roche, on the other hand, made the mistake of issuing a feel-good press release saying it supports greater transparency in clinical trials while sticking to its position of not releasing trial data.
For more on this story, or to sign the petition, go to alltrials.net, and to donate, go to http://www.justgiving.com/alltrials/eurl.axd/2fb898db34ec76479ab47c6c24a9eeb0. And please, spread the word to your social media contacts. This is a matter of importance to anyone who takes medicine.